Interleukin-17F expression is elevated in hepatitis C patients with fibrosis and hepatocellular carcinoma

The role of interleukin (IL) 17A in chronic liver diseases had been extensively studied, but the function of IL-17F, which shares a high degree of homology with IL-17A, in the progression of chronic hepatic di…

from #Cancer-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2uxLbeD
via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Interleukin-17F expression is elevated in hepatitis C patients with fibrosis and hepatocellular carcinoma

Palliative care physicians ’ experiences of end‐of‐life communication: A focus group study

The aim of this study was to explore palliative home care physicians’ experiences regarding end‐of‐life breakpoint communication (BPC). This is a qualitative study where focus group interviews were conducted and analysed using qualitative content analysis. The results show that the participants saw themselves as being responsible for accomplishing BPC, and they were convinced that it should be regarded as a process of communication initiated at an early stage, i.e. proactively. However, BPC was often conducted as a reaction to the patient’s sudden deterioration or sometimes not at all. The barriers to achieving proactive BPC included physicians’ uncertainty regarding the timing of BPC, primarily due to difficulties in prognostication in terms of time of death, and uncertainty as to…

from #Cancer-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2v82wfJ
via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Palliative care physicians ’ experiences of end‐of‐life communication: A focus group study

Exploring the provision of alcohol advice by clinicians to breast cancer patients

This study aimed to explore the extent and nature of clinician–patient discussions regarding alcohol intake and cancer outcomes in the clinical breast cancer setting, using a qualitative research design involving semi‐structured interviews. Purposive sampling was used to recruit 27 breast cancer clinicians (eight dietitians, nine breast care nurses, 10 oncologists) across Victoria, Australia. Interview data were analysed using descriptive statistics and a content analysis approach. Clinicians’ knowledge of national alcohol recommendations was found to be inconsistent. Clinicians reported a lack of patient awareness of the link between alcohol and breast cancer. Current frameworks for assessing and advising on patient alcohol intake were felt to be impractical. The extent and nature o…

from #Cancer-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2v7WZ8P
via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Exploring the provision of alcohol advice by clinicians to breast cancer patients

Developing an aftercare decision aid; assessing health professionals’ and patients’ preferences

Abstract Personalising aftercare for curatively treated breast cancer patients is expected to improve patient satisfaction with care. A patient decision aid can support women in making decisions about their aftercare trajectory, but is currently not available. The aim of this study was to assess the needs of patients and health professionals with regard to an aftercare decision aid to systematically develop such a decision aid. Focus groups with patients and individual interviews with health professionals were digitally recorded and coded using the Framework analysis. Although most patients felt few aftercare options were available to them, health professionals reported to provide various options on the patients’ request. Patients reported difficulty in expressing their need for options to…

from #Cancer-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2w07TK4
via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Developing an aftercare decision aid; assessing health professionals’ and patients’ preferences

Combining intraoperative imaging with PET scans helps surgeons identify malignant nodules

Surgeons were able to identify and remove a greater number of cancerous nodules from lung cancer patients when combining intraoperative molecular imaging (IMI) – through the use of a contrast agent that makes tumour cells glow during surgery – with…

from #Cancer-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2uZ7daG
via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Combining intraoperative imaging with PET scans helps surgeons identify malignant nodules

Trimethylamine N ‐oxide (TMAO): breathe new life

Abstract Associations between an elevated level of systemic trimethylamine N‐oxide (TMAO) and an increased risk for adverse cardiovascular events have been proposed in recent years. Increasing experimental studies suggest a possible impact of TMAO in cardiovascular diseases. TMAO, the oxygenated product of TMA, is belonging to the class of amine oxides. Most of TMA derived from the bacterial metabolism of choline and L‐carnitine is absorbed into the bloodstream, and then TMA is rapidly oxidized to TMAO by flavin‐containing monooxygenase‐3 (FMO3), a hepatic enzyme. Recent years, there has been considerable interest in the role of TMAO in various pathological states. Here we discuss the biosynthesis of TMAO and emerging clinical studies that have assessed TMAO as a biomarker for vari…

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from #Cancer-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/2uxH8yT
via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Trimethylamine N ‐oxide (TMAO): breathe new life