Society News AAOOP

Ocul Oncol Pathol 2018;4:66 (Source: Ocular Oncology and Pathology)

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Society News AAOOP

Liquid biopsies in gastrointestinal malignancies: when is the big day?

Authors: Lopez A, Harada K, Mizrak Kaya D, Dong X, Song S, Ajani JA Abstract INTRODUCTION: Tumor tissue sample is currently the gold standard for diagnosing gastrointestinal cancers, but also for genomic/immune component analyses that can help in the selection of therapy. However, this approach of studying a ‘representative’ sample of the tumor does not address inherent heterogeneity. Liquid biopsies, mainly represented by circulating tumor cells, circulating tumor DNA, tumor exosomes, and microRNAs, have the potential to assess various biomarkers for early detection of cancer, carrying out genomic/immune profiling for not only selection of appropriate therapy but also to monitor effect of therapy. Areas covered: This review summarizes the current evidence in the literature on liqu…

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Liquid biopsies in gastrointestinal malignancies: when is the big day?

Prospective studies on decompressive craniotomy for malignant MCA infarctions in Brazil: ready for prime time

ABSTRACT The Argentinian author Silvina Ocampo (1903-1993) left us a vast body of works which are considered outstanding in many ways. In 1960, she published a short story, entitled “ El m édico encantador» (The Charming Physician), in the renowned literary magazine Sur. The central character of this piece is a family doctor named Albino Morgan, who had a secret truth: in any house he visited, all variety of disease also entered. He brought with him the viruses he disseminated. The n arrator of this short story — one of his patients — describes four of Morgan’s diseases. These imaginary neurological conditions allowed Ocampo to explore improbable situations in everyday life.RESUMO A autora argentina Silvina Ocampo (1903-1993) deixou-nos uma vasta obra que é considerada excelente de…

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Prospective studies on decompressive craniotomy for malignant MCA infarctions in Brazil: ready for prime time

A novel muscle-sparing high thoracotomy for upper thoracic spine resection and reconstruction

ConclusionsThe described muscle-sparing, high thoracotomy approach provides excellent exposure of the ventral cervicothoracic and upper thoracic spine without the morbidity associated with the transection of shoulder girdle muscle bellies. This technique is particularly useful in patients with primary malignant bone tumors requiring en bloc excision and metastatic tumors with large soft tissue components. (Source: European Spine Journal)

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A novel muscle-sparing high thoracotomy for upper thoracic spine resection and reconstruction

Impact of tumor size on the prognosis of hepatocellular carcinoma in patients who underwent liver resection

Conclusion Tumor size ≥5 cm might be a good predicting factor for death and early recurrence when considering death as a competing risk. (Source: Journal of the Chinese Medical Association)

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Impact of tumor size on the prognosis of hepatocellular carcinoma in patients who underwent liver resection

Low-dose CT for lung cancer screening: opportunities and challenges

AbstractLung cancer is among the most frequently diagnosed cancers worldwide and the leading cause of cancer death in both males and females. Screening for lung cancer coupled with earlier intervention has long been studied as an approach to mortality reduction. However, minimal progress was achieved until recently, when lowdose spiral computed tomography (LDCT) screening demonstrated a 20% reduction in mortality from lung cancer in a randomized controlled trial (RCT), the National Lung Screening Trial, from the United States. On the basis of this finding, LDCT has been recommended for lung cancer screening in high-risk populations by several clinical guidelines. However, results from the following independent RCTs in Europe failed to show consistent conclusions. In addition, intractable p…

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Low-dose CT for lung cancer screening: opportunities and challenges