Sinusoidal obstruction syndrome (VOD/SOS), previously known as veno-occlusive disease (VOD), is an established complication in patients undergoing haemopoietic stem cell transplantation (HSCT). VOD/SOS is associated with the intensity of conditioning regimens used in HSCT but has also been reported in patients receiving standard chemotherapy.[1–3] It has been reported that there is a higher incidence of VOD/SOS associated with allogeneic transplant compared to autologous transplant, even when the conditioning regimens are similar.
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