The oral multikinase inhibitor regorafenib improves progression-free survival for patients with refractory advanced gastric adenocarcinoma, according to new research by Nick Pavlakis (University of Sydney, Sydney, NSW, Australia) and colleagues. The multinational, randomised phase 2 trial assessed 147 patients with gastric adenocarcinoma who had previous undergone chemotherapy. 97 patients were randomly assigned to supportive care plus regorafenib, and 50 patients were assigned to supportive care plus placebo.
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