EpiCast Report: Head and Neck Cancers – Epidemiology Forecast to 2024 – PR Newswire (press release)

EpiCast Report: Head and Neck Cancers – Epidemiology Forecast to 2024
PR Newswire (press release)
Head and neck cancers (HNCs) are a heterogeneous group, consisting of cancers of the mouth, including the lip, tongue, gum, floor of mouth, palate, and other parts of mouth; the salivary glands; the pharynx, including the tonsil, oropharynx

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EpiCast Report: Head and Neck Cancers – Epidemiology Forecast to 2024 – PR Newswire (press release)

• H. pylori infection induces the emergence of CSC-like properties in gastric cancer cells.• H. pylori activated the Wnt/β-catenin signaling pathway in a CagA-dependent manner and that the activation of this pathway was dependent upon the H. pylori-mediated phosphorylation of β-catenin at the C-terminal Ser675 and Ser552 residues in a c-met- and/or Akt-dependent manner.• Wnt/β-catenin signaling activation is responsible for the H. pylori-induced CSC-like properties.• H. pylori-activated Wnt/β-catenin signaling promotes the promoter activity of Nanog and Oct4 and upregulates their expression.

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Epithelial–mesenchymal transition-related genes are linked to aggressive local recurrence of hepatocellular carcinoma after radiofrequency ablation

• Aggressive progression in residual liver tumors after RFA was studied• We focused on epithelial–mesenchymal transition (EMT)-related genes and miRNAs• Increased expression of EMT-related genes was through down-regulation of miRNAs

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Epithelial–mesenchymal transition-related genes are linked to aggressive local recurrence of hepatocellular carcinoma after radiofrequency ablation

Multiple cellular origins and molecular evolution of intrahepatic cholangiocarcinoma

• ICC is a heterogeneous cancer in epidemiology, morphology, pathology and molecular biology.• Cancer cell origin affects tumor cell fate and ICC phenotype.• Cancer cell origin can be accurately determined based on the Roadmap Epigenomics Program.• Increased understanding of cell origin may contribute to establishment of a hierarchical model of ICC carcinogenesis.

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Multiple cellular origins and molecular evolution of intrahepatic cholangiocarcinoma

GZD856, a novel potent PDGFRα/β inhibitor, suppresses the growth and migration of lung cancer cells and

Lung cancer remains the leading cause of cancer death worldwide, despite of the recent significant progress on chemotherapies, immunotherapies and kinase inhibitor drugs. Inhibition of PDGFRs represents a new promising strategy for human lung cancer management by targeting both autocrine-stimulated cancer cell growth and/or recruitment of cancer-associated stromal fibroblasts (CAFs).In this paper, we report the the discovery of GZD856 as new PDGFRα/β inhibitor.1) The compound potently inhibits the kinase activities of PDGFRα/β and dose dependently blocks the PDGFRα/β signaling pathway in lung cancer cells.

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GZD856, a novel potent PDGFRα/β inhibitor, suppresses the growth and migration of lung cancer cells and

EpiCast Report: Head and Neck Cancers – Epidemiology Forecast to 2024 – PR Newswire (press release)

EpiCast Report: Head and Neck Cancers – Epidemiology Forecast to 2024
PR Newswire (press release)
It includes a 10-year epidemiological forecast of the diagnosed incident cases of HNCs segmented into three sub-groups: cancers of the lip, oral cavity, and pharynx; cancers of the nose, sinuses, and related structures; and cancers of the larynx, in
Head and Neck Cancers Market 2024 Global Forecast and AnalysisDigital Journal

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EpiCast Report: Head and Neck Cancers – Epidemiology Forecast to 2024 – PR Newswire (press release)

Capitol Intrigue: Feb. 29 – Tallahassee.com

images?q=tbn:ANd9GcT-uA9dO1nJD0JjXYKlFWy5Hne352rM7-mWc63BVMLe9i8rcmswrCLhCF4mZWu9bZj6CG0tOuzQ
Tallahassee.com
Capitol Intrigue: Feb. 29
Tallahassee.com
The organizations included the Cancer Action Network, AIDS Healthcare Foundation, Florida Medical Association, Florida Public Health Association, Nemours Children’s Hospital System and Council of Medical School Deans. Abortion restrictions … The

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Capitol Intrigue: Feb. 29 – Tallahassee.com